May 26, 2010

Regrowing Teeth

This is a pretty cool technology that should be hitting the market in the next couple of years (barring extreme nanny state bullshit):

Dr. Jeremy Mao, the Edward V. Zegarelli Professor of Dental Medicine at Columbia University Medical Center, has unveiled a growth factor-infused, three-dimensional scaffold with the potential to regenerate an anatomically correct tooth in just nine weeks from implantation. By using a procedure developed in the university's Tissue Engineering and Regenerative Medicine Laboratory, Dr. Mao can direct the body's own stem cells toward the scaffold, which is made of natural materials. Once the stem cells have colonized the scaffold, a tooth can grow in the socket and then merge with the surrounding tissue.

Dr. Mao's technique not only eliminates the need to grow teeth in a Petri dish, but it is the first to achieve regeneration of anatomically correct teeth by using the body's own resources. Factor in the faster recovery time and the comparatively natural process of regrowth (as opposed to implantation), and you have a massively appealing dental treatment.

Awesome.  Now, get moving on similar technology for organs.  My favorite part of the huge stem cell argument was that those opposed to fetal stem cells were saying, "there's got to be another way" and a bunch of closed-minded people said, "impossible!" 

There were, in fact, many better ways.

Posted by: Moron Pundit at 11:12 AM | Comments (16) | Add Comment
Post contains 224 words, total size 2 kb.

1 My understanding is that there hasn't yet been a single treatment made workable by use of fetal stem cells.  Am I mistaken?

Posted by: Wolfwood at May 26, 2010 01:55 PM (qNLRw)

2 I always check and, while the "journalists" always try to obfuscate the issue, they are almost always not embryonic stem cells.

I do recall seeing one thing where they were listed as possibly being useful, but all the concrete breakthroughs are from other ones that don't require destroying an embryo.

Posted by: Veeshir at May 26, 2010 02:16 PM (NrODv)

3 My understanding is that there hasn't yet been a single treatment made workable by use of fetal stem cells.  Am I mistaken?

I last checked on that about four months ago and I believe that was still the case at that time. 

Posted by: alexthechick at May 26, 2010 02:17 PM (8WZWv)

4 Sometime a while back I read a story about a breakthrough where they could cause nearly any cell anywhere in the body to demonstrate stem cells with a  certain manipulation.  I knew after that the embryonic stem cells would be useless.  Of course, it was all crickets from the loudmouthed tard scientists about the issue but I've noted that the argument has all be disappeared from the news.

Posted by: Moron Pundit at May 26, 2010 03:25 PM (GC5S2)

5

Three years to approove the treatment, five years before insurance covers it.  Eight years for the price to come down a bit, and ten years before the TOOTH SHACK open at every walmart super store with $50 Tooth-buds-while-you-wait. 

Barring that nannotocracy (nanacracy?) thing, yeah.

 

Posted by: vermindust at May 26, 2010 11:00 PM (E0ruc)

6 This is a pretty cool technology indeed, and this sentence pretty much says it all. However, this sentence 'Dr. Mao can direct the body's own stem cells toward the scaffold' made me laught a bit, I don't know why. Anyway, it's a nice site, so don't stop.

Posted by: Jack at May 29, 2010 05:09 PM (A1v70)

7 Hey, FYI it's going to take a bit more time than that. Dr. Mao's work is currently in the pre-clinical phase, where animal trials are conducted and research is done. This part seems to have concluded with the announcement above, meaning that now they have to start planning for human trials, which takes an additional 2-3 years. Then, in the US, there are 3-4 trial phases, as per the FDA. In Phase 1, the first human subjects are used. In Phase 2, a larger group of several hundred might be used. In Phase 3, several thousand patients may be used and the work conducted by multiple teams in different labs. At this point, if all goes well, the drug (or procedure) generally goes to the FDA for approval, which is an arduous process in an of itself. Each one of these trial periods, however, can easily take 4-5 years to complete, as the research must be conducted, studied, presented, then reviewed. The animal portions are a bit easier to conduct, but the the human portions, for obvious reasons, have a lot more restrictions and guidelines placed on them. I'd love to think that this technology can hit the market within 10-12 years, but it's not unreasonable to think that it'll be 15-20 years before someone can walk into a doctors office and feasibly discuss it.

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